About the autoimmune disease lupus - systemic lupus erythematosus or "SLE"

Centers for Disease Control and Prevention (CDC)

Systemic lupus erythematosus or SLE, often just called lupus, is a long-term autoimmune disease. This means the body’s immune system attacks its own healthy cells and tissues, leading to inflammation that could damage organs or systems. It is long-term (chronic) disease that affects many different parts of the body.

There can be many different signs and symptoms of lupus, which makes it difficult to diagnose. Lupus has no cure, but medicines and lifestyle changes can help treat and manage it.
Symptoms can range from mild to life-threatening.

There is no cure for lupus, but it can be treated. The earlier lupus is diagnosed, the better it can be treated and managed.

Causes

The causes of lupus are not known, but the cause or causes may be linked to a person’s environment, family history (genetics), or hormonal factors.

Family History

If you have a close family member with lupus, your risk of getting it may be slightly higher than others. Some people with lupus have relatives with lupus, but most people with lupus do not have family members who also have the disease.

Diagnosis

Lupus can be hard to diagnose since its symptoms are often mistaken for symptoms of other diseases.

A rheumatologist can diagnose lupus. A rheumatologist is a doctor who specializes in painful conditions affecting the body’s joints, muscles, or connective tissues — like lupus.

There is no one test for lupus, but your doctor will most likely discuss your symptoms, give you a physical examination, take X-rays, and run lab tests.

How to manage symptoms

Since lupus symptoms vary widely from person to person, the way it’s managed depends on each person’s symptoms and needs. To best manage your symptoms, it is important to see a doctor regularly, take medicines as prescribed, and follow your treatment plan.

Staying Healthy

Making healthy choices and learning how to manage your care can help you have a healthier and better quality of life. Make healthy choices. For example, people with lupus should:
• Be physically active.
• Eat healthy foods.
• Get plenty of rest.
• Avoid smoking cigarettes.
• Use sunscreen and avoid too much sun.
• Learn self-care skills. Self-management education can help people with lupus learn the skills needed to:
       • Manage daily life activities.
       • Take medications as prescribed.
       • Better communicate with doctors.
       • Take steps to improve energy.
       • Better manage pain.

Treatment and recovery

The goals of treatment are to:
• Prevent future increases in symptoms (flare-ups).
• Stop or delay damage to joints and organs.
• Reduce inflammation.

A team approach

A team of specialist may work together on your treatment. This approach is important because lupus has many different symptoms, and people with lupus may have other autoimmune conditions as well. The team of specialists may include:
• Primary care providers.
• Rheumatologists.
• Pain management specialists.
• Physical therapists.

Medications to treat lupus

The main treatment for lupus involves using medications that suppress the immune system. These may include:
• Hydroxychloroquine, a medicine also used to treat malaria.
• Corticosteroids, medicines that reduce inflammation and affect the body’s immune system, such as prednisone.
• Biologics, medicines made from living organisms, like belimumab and rituximab.

Things that worsen the effects of lupus

Certain things can worsen lupus, increasing flares and possibly a person’s risk of death. These things include not having access to health care, having lupus for a long time before being diagnosed with it, and not following a treatment plan.